Nonlinear pressure-flow relationships for passive microfluidic valves.

نویسندگان

  • Erkin Seker
  • Daniel C Leslie
  • Hossein Haj-Hariri
  • James P Landers
  • Marcel Utz
  • Matthew R Begley
چکیده

An analytical solution is presented for the nonlinear pressure-flow relationship of deformable passive valves, which are formed by bonding a deformable film over etched channels separated by a weir. A fluidic pathway connecting the channels is opened when the upstream pressure creates a tunnel along a predefined narrow strip where the film is not bonded to the weir. When the width of the strip is comparable to the inlet channel width, the predicted closed-form pressure-flow rate relationship is in excellent agreement with experiments, which determine pressures by measuring film deflections for prescribed flow rates. The validated closed-form models involve no fitting parameters, and provide the foundation to design passive diodes with specific nonlinear pressure-flow characteristics.

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عنوان ژورنال:
  • Lab on a chip

دوره 9 18  شماره 

صفحات  -

تاریخ انتشار 2009